Formulations, dosing, supply and the business of medicines made for children.
A tablet that suits a 70kg adult is often useless for a toddler. Getting the dose, the taste and the ingredients right is a development programme in its own right.
Medicines
The liquid medicine is losing its monopoly. Flexible solid formats promise better stability, more accurate dosing and lower costs, especially outside rich countries.
Medicines
Children are not small adults, and dosing them by simple arithmetic from adult doses can go badly wrong. The science of getting it right starts with how the body matures.
Medicines
Preservatives, solvents and sweeteners rarely make headlines. In the youngest patients, they can matter as much as the active drug.
Medicines
The winter of 2022 exposed how thin the supply of basic paediatric antibiotics had become. The structural reasons have not gone away.
Medicines
Biosimilars can win approval for paediatric uses without paediatric trials. The bigger practical issue is often whether the right dose and device exist for a small child.
